Neuroimmune pharmacological approaches

Pharmacological Approaches to Stuttering

Purpose: To address questions raised by T. Meline andW. E. Harn (2008) in their critique of our previous article (A. K. Bothe, J. H. Davidow, R. E. Bramlett, D. M. Franic, & R. J. Ingham, 2006). Method: Additional information is provided to address several issues raised by Meline and Harn. Results and Conclusions: Our previous systematic review omitted 1 relevant article about the use of olanza...

Headache management: pharmacological approaches

Headache is one of the most common conditions presenting to the neurology clinic, yet a significant proportion of these patients are unsatisfied by their clinic experience. Headache can be extremely disabling; effective treatment is not only essential for patients but is rewarding for the physician. In this first of two parts review of headache, we provide an overview of headache management, em...

Pharmacological approaches to smoking cessation.

Smoking, the most prominent nongenetic factor contributing to mortality, remains the major public health problem throughout the world. There are nearly 1.1 billion users of nicotine and tobacco products worldwide while approximately one third to half of them will die from smoking-related disease. The habit of smoking is mainly propelled by nicotine, a strongly addictive substance, to which the ...

Pharmacological Approaches to Improve Ageing

Pharmacological approaches to antitrypanosomal chemotherapy.

There is an urgent need for new drugs for the chemotherapy of human African trypanosomiasis, Chagas disease and leishmaniasis. Progress has been made in the identification and characterization of novel drug targets for rational chemotherapy and inhibitors of trypanosomatid glycosomal enzymes, trypanothione reductase, ornithine decarboxylase, S-adenosylmethionine decarboxylase, cysteine protease...